Federal Personal Defense, 410 Gauge 2.5, 000 Buck, Buckshot, 4 Pellets, 20 Round Box, Designed for Handgun PD412JGE000 The .410 handgun has emerged as a popular option for self-defense, and Federal Premium offers a variety of loads for these specialized firearms. A customized hull design, optimal brass thickness and fine-tuned payloads make these perfect for .410 handguns.